TP-145

GENETIC VARIATION IN ABC-TRANSPORTERS MODIFY METHYLMERCURY DISPOSITION

Authors: ENGSTRÖM, Karin 1 ; LLOP, Sabrina 2 ; LOVE, Tanzy 3 ; RAND, Matthew 4 ; SHAMLAYE, Conrad 5 ; SOFIANOU-KATSOULIS, Aikaterini 6 ; BARBONE, Fabio 7 ; BALLESTER, Ferran 2 ; VAN WIJNGAARDEN, Edwin 3 ; BROBERG, Karin 8 ;
(1) Lund University, Lund, Sweden; (2) FISABIO−Universitat Jaume I−Universitat de València, Valencia, Spain; (3) School of Medicine and Dentistry, University of Rochester, Rochester, USA; (4) University of Rochester, Rochester, USA; (5) Child Development Centre, Ministry of Health, Mahé, Seychelles; (6) Department of Social and Developmental Paediatrics Institute of Child Health, Athens, Greece; (7) Department of Medical and Biological Sciences, University of Udine, Udine, Italy; (8) Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden

TP-146

ALTERNATIVE TESTING METHODS: COMPARING TEST SENSITIVITIES BETWEEN FISH EMBRYO AND FISH CELL MODELS

Authors: ALLOY, Matthew 1 ; BARST, Benjamin 1 ; BASU, Niladri 1 ;
(1) McGill University, Sainte Anne de Bellevue/Quebec, Canada

TP-147

METHYLMERCURY-INDUCED OXIDATIVE DAMAGE IN LIVER, KIDNEY AND BRAIN OF RATS: PROTECTION BY N-ACETYL CYSTEINE AND SELENIUM

Authors: JOSHI, DEEPMALA 1 ; BELEMKAR, SATEESH 1 ;
(1) Shri Vile Parle Kelavani Mandal’s (SVKM's), Narsee Monjee Institute of Management Studies (NMIMS), Shirpur, Shirpur/ Maharashtra, India

TP-149

MERCURY-INDUCED EPIGENETIC TRANSGENERATIONAL INHERITANCE OF ABNORMAL NEUROBEHAVIOR IS CORRELATED WITH SPERM EPIMUTATIONS AND DYSREGULATED BRAIN AND RETINA GENE EXPRESSION IN ZEBRAFISH

Authors: CARVAN III, M . 1 ; KALLUVILA, T . 2 ; KLINGLER, R . 1 ; LARSON, J . 1 ; PICKENS, M . 1 ; MORA-ZAMORANO, F . 1 ; CONNAUGHTON, V . 3 ; SADLER-RIGGLEMAN, I . 4 ; BECK, D . 4 ; SKINNER, M . 4 ;
(1) School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI, USA; (2) Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA; (3) Department of Biology, American University, Washington, DC, USA; (4) Center for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA, USA

TP-151

PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING OF METHYLMERCURY IN YOUNG RINGED SEALS

Authors: EWALD, Jessica 1 ; LI, Miling 1 ; BASU, NILADRI 2 ; KIRK, Jane 3 ; ISLAM, Naima 3 ; MUIR, Derek 3 ; SUNDERLAND, Elsie 1 ;
(1) Harvard University, Cambridge, MA, USA; (2) McGill University, Montreal, Quebec, Canada; (3) Environment and Climate Change Canada, Burlington, ON, Canada

TP-152

THE EFFECTS OF METHYLMERCURY ON BREAST CANCER CELLS

Authors: GAUDET, Hilary 1 ; CHRISTENSEN, Emily 1 ; CONN, Brandon 1 ; MORROW, Sara 1 ; ZHANG, Raymond 1 ; BENOIT, Janina 1 ;
(1) Wheaton College, Norton, MA, United States

TP-153

IMPACT OF METHYLMERCURY IN HYPOSTOMUS GYMNORHYNCHUS AND HOPLIAS AIMARA HARVESTED IN PRISTINE AND CONTAMINATED SITES FROM THE OYAPOCK RIVER IN FRENCH GUIANA

Authors: GONZALEZ, Patrice 1 ; MAURY-BRACHET, Régine 1 ; GENTES, Sophie 1 ; BAUDRIMONT, Magalie 1 ; LEGEAY, Alexia 1 ; FEURTET-MAZEL, Agnès 1 ; DAFFE, Guillemine 1 ; MESMER-DUDONS, Nathalie 1 ; MAURICE, Laurence 2 ;
(1) University of Bordeaux, Arcachon, France; (2) IRD, Toulouse, France

TP-154

TOXICOKINETICS OF MERCURY IN THE HUMAN PLACENTA: PRELIMINARY DATA ON RELATIONSHIPS BETWEEN GENOTYPE AND PHENOTYPE IN HEALTHY AND DISEASED PLACENTA

Authors: GRANITZER, Sebastian 1 ; STRAKA, Elisabeth 1 ; ELLINGER, Isabella 1 ; ZEISLER, Harald 1 ; SALZER, Hans 2 ; HENGSTSCHLÄGER, Markus 1 ; GUNDACKER, Claudia 1 ;
(1) Medical University of Vienna, Vienna, Austria; (2) University Hospital Tulln, Tulln, Austria

TP-155

CHARACTERIZATION OF MERCURY-BINDING PROTEINS IN RAT BLOOD

Authors: HU, Ligang 1 ;
(1) RCEES, CAS, Beijing, China

TP-156

DIFFERENT EFFECTS OF METHYLMERCURY EXPOSURE ON LOCOMOTOR BEHAVIORS IN ADULT MALE AND FEMALE ZEBRAFISH (DANIO RERIO)

Authors: BENOIT, Janina 1 ; KIRKPATRICK, Meg 1 ; BAUER, Jordan 1 ;
(1) Wheaton College, Norton, MA, USA

TP-157

ARE MATERNAL STOOL SAMPLES A VALID BIOMARKER FOR PRENATAL METHYLMERCURY EXPOSURE?

Authors: MCCALLA, Carly 1 ; WAGNER, Carol 2 ; DONOHUE, Alexis 1 ; ROTHENBERG, Sarah 1 ;
(1) University of South Carolina, Columbia, SC, United States; (2) Medical University of South Carolina, Charleston, SC, United States

Abstract not available.

TP-158

DEVELOPMENT OF AN ECOPHYSIOLOGICAL DAPHNIA MODEL TO EXAMINE THE INTERACTIVE EFFECTS OF NUTRITION AND METHYLMERCURY TOXICITY

Authors: NI, Felicity 1 ; KELLY, Noreen 1 ; ARHONDITSIS, George 1 ;
(1) University of Toronto, Toronto, Ontario, Canada

TP-159

ELUCIDATING THE BIOCHEMICAL EFFECTS OF MERCURY EXPOSURE IN AN ENVIRONMENTAL SENTINEL WITH METABOLOMICS AND EPIGENETICS TECHNIQUES

Authors: NILSEN, Frances 1 ; SCHWENTER, Jefferey 2 ; DAY, Russel 3 ; PARROTT, Ben 4 ; BOWDEN, John 3 ; LONG, Stephen 3 ; SCHOCK, Tracey 3 ;
(1) NIST/MUSC, Charleston, SC, USA; (2) Grice Marine Lab, College of Charleston, SC, Charleston, SC, USA; (3) NIST, Charleston, SC, USA; (4) University of Georgia, Athens, GA, USA

TP-160

UNVEILING COPING STRATEGIES WITH MERCURY IN AQUATIC AND SEMI-AQUATIC INHABITANTS

Authors: PEREIRA, Eduarda 1 ; ANJUM, Naser 1 ; COELHO, João 1 ; VALE, Carlos 2 ; DUARTE, Armando 1 ; FIGUEIRA, Paula 3 ;
(1) CESAM & Chemistry Department, University of Aveiro, Aveiro, Portugal; (2) CIIMAR, University of Porto, Porto, Portugal; (3) CICECO & Chemistry Department, University of Aveiro, Aveiro, Portugal

TP-162

THE BIOCHEMISTRY OF THE FIVE “SOS” MECHANISMS OF MERCURY TOXICITY

Authors: RALSTON, Nicholas 1 ; RAYMOND, Laura 2 ;
(1) University of North Dakota, Grand Forks, ND, USA; (2) Translational Medicine Independent Research Consultants, Grand Forks, ND, USA

TP-163

PROTEOME OF PRIMARY ASTROCYTES INDICATE A CENTRAL ROLE OF OXIDATIVE INJURY EXPOSED BY MEHG

Authors: SHAO, Yueting 1 ; WANG, Lewis 2 ; LANGLOIS, Patrick 1 ; CHAN, Laurie 1 ;
(1) University of Ottawa, Ottawa/Ontario, Canada; (2) St. George's University, St. George's, Grenada

TP-164

EFFECTS ON PROLACTIN (PRL) ON CYTOTOXITY INDUCED BY METHYLMERCURY IN HUMAN LYMPHOCYTES AND HUMAN PROMYELOCYTIC LEUKEMIA CELL HL60, BOTH IN VITRO.

Authors: SILVA-PEREIRA, Liz 1 ; RODRIGUEZ BURBANO, Rommel 2 ;
(1) Institute of Education, Science and Tecnology of Pará, IFPA, Itaituba College, Itaituba Pará, Brazil; (2) University of Pará, Belém Pará, Brazil

TP-165

TOXICOKINETICS OF MERCURY DEMETHYLATION: MERCURY ACCUMULATION AND SPECIATION IN THE LIVERS OF MARINE AND FRESHWATER FISH SPECIES

Authors: SOULEN, Brianne 1 ; BARST, Benjamin 2 ; BRIDGES, Kristin 1 ; DREVNICK, Paul 3 ; ROBERTS, Aaron 1 ;
(1) Department of Biology, Advanced Enivronmental Research Institute, University of North Texas, Denton, TX, USA; (2) Environmental Health Sciences Lab, McGill University, Ste-Anne-de-Bellevue, Quebec, Canada; (3) Environmental Monitoring and Science Division, Alberta Environment and Parks, Calgary, Alberta, Canada

TP-166

PROTEOMIC AND TRANSCRIPTOMIC INSIGHTS INTO CELLULAR AND MOLECULAR DAMAGE AND RECOVERY FROM INORGANIC AND ORGANIC HG EXPOSURE IN A MODEL MICROORGANISM

Authors: LAVOIE, Stephen 1 ; WIGGINS, Andrew 1 ; SUMMERS, Anne 1 ;
(1) University of Georgia, Athens, Georgia, USA

TP-167

EVALUATION OF NEUROBEHAVIORAL DISORDERS IN METHYLMERCURY-EXPOSED KK-AY MICE BY DYNAMIC WEIGHT BEARING TEST

Authors: YAMAMOTO, Megumi 1 ; MOTOMURA, Eriko 1 ; YANAGISAWA, Rie 2 ; HOANG, Van 3 ; MOGI, Masaki 4 ; MORI, Tomohisa 5 ; NAKAMURA, Masaaki 1 ; TAKEYA, Motohiro 6 ; ETO, Komyo 7 ;
(1) National Institute for Minamata Disease, Minamata, Japan; (2) National Institute for Environmental Studies, Tsukuba, Japan; (3) National Institute for Minamata Disease & Prefectural University of Kumamoto, Minamata, Japan; (4) Ehime University, Toon, Japan; (5) Hoshi University, Tokyo, Japan; (6) Kumamoto University, Kumamoto, Japan; (7) Health and Nursing Facilities for the Aged, Jushindai, Tamana, Japan

TP-168

MATERNAL TRANSFER OF MERCURY IN THE BLOOD OF ORGANISMS STANDING ON THE TOP OF TROPHIC CHAIN

Authors: GRAJEWSKA, Agnieszka 1 ; FALKOWSKA, Lucyna 1 ; NEHRING, Iga 1 ; OSOWSKA, Natalia 1 ; STANISZEWSKA, Marta 1 ; SANIEWSKA, Dominika 1 ; PAWLICZKA, Iwona 2 ;
(1) Department of Marine Chemistry and Environmental Protection, Institute of Oceanography, University of Gdansk, Gdynia, Poland; (2) Hel Marine Station Institute of Oceanography University of Gdansk, Hel, Poland

TP-169

THE INFLUENCE OF LIFE HISTORY AND DIET ON MERCURY BIOACCUMULATION AND BIOMAGNIFICATION IN BLOOD OF BOTTLENOSE DOLPHINS, TURSIOPS TRUNCATUS, UNDER HUMAN CARE

Authors: SMITH, Julia 1 ; JENSEN, Brenda 1 ; CAMPBELL, Michelle 2 ; BRYAN, Colleen 3 ;
(1) College of Natural and Computational Sciences, Hawaii Pacific University, Kaneohe, HI, USA; (2) Dolphin Quest/Quest Global Management, San Diego, CA, USA; (3) Chemical Sciences Division, National Institute of Standards and Technology, Charleston, SC, USA

TP-170

FORMATION OF HGSE MICRO-DEPOSITS IN THE EYE AND INTERNAL EAR OF LONG-FINNED PILOT WHALES

Authors: KORBAS, Malgorzata 1 ; HOYDAL, Katrin 2 ; DAM, Maria 2 ;
(1) Canadian Light Source, Saskatoon, Saskatchewan, Canada; (2) Environment Agency, Faroe Islands, Denmark